Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | CD44 | P16070 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31018417 | 0.81 | TEAD1 (0.52) | P2RY1CD44P2RX7PIK3CDPIK3C2B | |
| Hydrochloric Acid SCHEMBL31018396 | 0.80 | TEAD1 (0.51) | P2RY1CD44P2RX7PIK3CDPIK3C2B | |
| SCHEMBL31018391 | 0.76 | CD44 (0.40) | CD44CSF1RCDK4CDK6 | |
| SCHEMBL4868312 | 0.74 | APP (0.41) | APPEPHX2FAAHABL1BCR | |
| SCHEMBL31018399 | 0.72 | EPHX2 (0.40) | APPEPHX2FAAHABL1BCR | |
| SCHEMBL2847817 | 0.71 | APP (0.41) | APPEPHX2FAAHABL1BCR | |
| SCHEMBL31018406 | 0.70 | TEAD1 (0.51) | EPHX2ULK1TEAD1TEAD4TEAD2 | |
| SCHEMBL31018386 | 0.70 | ASIC3 (0.44) | CD44CSF1RCDK4CDK6P2RX7 | |
| SCHEMBL31474532 | 0.68 | EPHX2 (0.54) | EPHX2 | |
| SCHEMBL30592023 | 0.68 | EPHX2 (0.54) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4654969-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024159067-A1 | COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR | Opna Bio SA (CH) | 2024-08-02 | — | — | WO | disclosed |