Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21957547 | 1.00 | NPC1 (0.45) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL21957549 | 1.00 | NPC1 (0.45) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL16620449 | 0.84 | CA2 (0.41) | NPC1SMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL17985136 | 0.84 | CA2 (0.41) | NPC1SMN1; SMN2LMNARAB9AMAPT | |
| SCHEMBL21957535 | 0.83 | SMN1; SMN2 (0.39) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL21957534 | 0.83 | SMN1; SMN2 (0.39) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL21957532 | 0.83 | NPC1 (0.50) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL21957533 | 0.83 | NPC1 (0.50) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL21957550 | 0.83 | NPC1 (0.50) | NPC1CASP3SENP8SENP7SENP6 | |
| SCHEMBL21957548 | 0.83 | NPC1 (0.50) | NPC1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052531-B1 | POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP | BRIDGESTONE CORP (JP) | 2024-07-24 | — | — | EP | disclosed |