Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494158 | 1.00 | LOXL2 (0.38) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL28587853 | 0.90 | LOXL2 (0.33) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL30608511 | 0.74 | CA12 (0.43) | CA12CA2CA9CA1 | |
| SCHEMBL22581461 | 0.74 | CA12 (0.43) | CA12CA2CA9CA1CA14 | |
| SCHEMBL27168866 | 0.73 | SSTR4 (0.38) | — | |
| SCHEMBL29911763 | 0.72 | — | — | |
| SCHEMBL4373859 | 0.72 | — | — | |
| SCHEMBL12557645 | 0.72 | LOXL2 (0.38) | LOXL2CA12CA2CA9CA1 | |
| SCHEMBL27685127 | 0.72 | SIRT3 (0.40) | — | |
| SCHEMBL28364429 | 0.72 | RPS6KA3 (0.30) | RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217500-A1 | ISOQUINOLINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2024-10-24 | — | — | WO | disclosed |
| CN-115003671-B | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2024-08-06 | — | — | CN | disclosed |