Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324922 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL2324613 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL28882232 | 0.87 | CSNK1D (0.45) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL12279519 | 0.87 | CSNK1D (0.45) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL14637930 | 0.84 | MEN1 (0.54) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL14633349 | 0.83 | MEN1 (0.58) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL17948454 | 0.82 | MEN1 (0.57) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL15206750 | 0.82 | MEN1 (0.43) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL15206749 | 0.82 | MEN1 (0.43) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL27892479 | 0.78 | MAPT (0.40) | ALDH1A1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003671-B | JNK inhibitors, pharmaceutical compositions and uses thereof | 武汉朗来科技发展有限公司 | 2024-08-06 | — | — | CN | disclosed |