Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768178 | 1.00 | DPP4 (0.39) | DPP4DPP8MEN1KMT2AESR1 | |
| SCHEMBL2123936 | 0.89 | CAMK2A (0.43) | DPP4DPP8MEN1KMT2AESR1 | |
| SCHEMBL31546529 | 0.89 | CAMK2A (0.43) | DPP4DPP8MEN1KMT2AESR1 | |
| SCHEMBL30997677 | 0.84 | NR1H2 (0.45) | DPP4DPP8ESR1ESR2HTR2A | |
| SCHEMBL14575206 | 0.84 | NR1H2 (0.45) | DPP4DPP8ESR1ESR2HTR2A | |
| SCHEMBL623843 | 0.83 | DPP4 (0.39) | DPP4DPP8KMT2ALMNACYP3A4 | |
| SCHEMBL29088742 | 0.82 | SMN1; SMN2 (0.45) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL19638457 | 0.82 | CAMK2A (0.47) | DPP4DPP8MEN1KMT2AESR1 | |
| SCHEMBL623616 | 0.82 | DPP4 (0.39) | DPP4DPP8MEN1KMT2ACYP3A4 | |
| SCHEMBL22366344 | 0.80 | MTNR1B (0.48) | NPSR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |