Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21202764 | 0.75 | ATM (0.50) | ALDH1A1NPC1RAB9A | |
| SCHEMBL6477443 | 0.75 | BACE1 (0.44) | GRM2BACE1LMNASMN1; SMN2NOS1 | |
| SCHEMBL17179173 | 0.74 | PARP1 (0.54) | GRM2BACE1ALDH1A1PARP1GABRA1 | |
| SCHEMBL6171961 | 0.71 | PARP1 (0.59) | GRM2BACE1ALDH1A1PARP1LMNA | |
| SCHEMBL7551886 | 0.70 | BACE1 (0.41) | GRM2BACE1ALDH1A1PRNPLMNA | |
| SCHEMBL12737723 | 0.69 | KDM4E (0.50) | ALDH1A1 | |
| SCHEMBL7983249 | 0.69 | BACE1 (0.56) | GRM2BACE1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10272995 | 0.67 | BACE1 (0.36) | BACE1ALDH1A1PARP1GABRA1GABRB2 | |
| SCHEMBL18424987 | 0.67 | PDE10A (0.39) | GRM2BACE1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29454726 | 0.66 | ALDH1A1 (0.40) | GRM2ALDH1A1PRNPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234724-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2024-06-21 | — | — | CN | disclosed |