Sugi Predict

Sugi Predict / Compounds / SCHEMBL31020751

SCHEMBL31020751

SCHEMBL31020751

NC(=O)CC[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DPP3 Q9NY33 5/20 0.59
▸ KISS1R Q969F8 4/20 0.57
▸ TACR1 P25103 1/20 0.56
▸ OPRM1 P35372 2/20 0.55
▸ CXCL8 P10145 5/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31746148 0.94 DPP3 (0.58) DPP3KISS1RTACR1OPRM1CXCL8
SCHEMBL29878538 0.92 TACR1 (0.62) DPP3KISS1RTACR1OPRM1
SCHEMBL29558373 0.91 CAPN1 (0.61) DPP3KISS1RTACR1CXCL8
SCHEMBL29845337 0.91 CXCR4 (0.58) KISS1RCXCL8
SCHEMBL29616317 0.90 DPP3 (0.61) DPP3KISS1RTACR1OPRM1
SCHEMBL30381557 0.89 KISS1R (0.59) DPP3KISS1RTACR1CXCL8
SCHEMBL31676682 0.88 DPP3 (0.56) DPP3KISS1RTACR1OPRM1
SCHEMBL29569487 0.88 TACR1 (0.59) DPP3TACR1OPRM1CXCL8
SCHEMBL30540269 0.87 DPP3 (0.61) DPP3KISS1ROPRM1
SCHEMBL29590460 0.87 F2 (0.56) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2847223-B2 ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME DARTMOUTH COLLEGE (US) 2025-04-09 — — EP disclosed
US-20250002584-A1 ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME DARTMOUTH COLLEGE (US) 2025-01-02 — — US disclosed
US-12065492-B2 Anti-B7-H6 antibody, fusion proteins, and methods of using the same THE TRUSTEES OF DARTMOUTH COLLEGE (US) 2024-08-20 — — US disclosed
CN-110511278-B Anti-B7-H6 antibodies, fusion proteins, and methods of use thereof 达特茅斯大学理事会 2024-08-09 — — CN disclosed