SCHEMBL31020752

CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)O)[C@@H](C)O

nearest known ligand 0.75

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.64

▸	NPY4R	P50391	8/20	0.64

▸	NPY5R	Q15761	8/20	0.64

▸	NPY1R	P25929	6/20	0.64

▸	KEAP1	Q14145	1/20	0.63

▸	EP300	Q09472	1/20	0.62

▸	HIF1A	Q16665	1/20	0.62

▸	NMUR2	Q9GZQ4	3/20	0.62

▸	NMUR1	Q9HB89	3/20	0.62

▸	TFPI	P10646	2/20	0.62

▸	CALCR	P30988	1/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31182450	0.96	NPY2R (0.66)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30432021	0.92	NPY2R (0.68)	NPY2RNPY4RNPY5RNPY1RKEAP1
SCHEMBL30512723	0.92	NPY2R (0.59)	NPY2RNPY4RNPY5RNPY1RKEAP1
Sptcipsgqpcpynenccsqsctfkenengntvkrcd SCHEMBL29695388	0.91	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1REP300
Sstcipsgqpcpynenccsqsctykenengntvkrcd SCHEMBL29838759	0.91	NPY2R (0.67)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30495808	0.91	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30423064	0.91	KEAP1 (0.69)	NPY2RNPY4RNPY5RNPY1RKEAP1
SCHEMBL30495583	0.90	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31230205	0.90	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RKEAP1
SCHEMBL29463778	0.90	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1RKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2847223-B2	ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME	DARTMOUTH COLLEGE (US)	2025-04-09	—	—	EP	disclosed
US-20250002584-A1	ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME	DARTMOUTH COLLEGE (US)	2025-01-02	—	—	US	disclosed
US-12065492-B2	Anti-B7-H6 antibody, fusion proteins, and methods of using the same	THE TRUSTEES OF DARTMOUTH COLLEGE (US)	2024-08-20	—	—	US	disclosed
CN-110511278-B	Anti-B7-H6 antibodies, fusion proteins, and methods of use thereof	达特茅斯大学理事会	2024-08-09	—	—	CN	disclosed