Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21617958 | 1.00 | LOXL2 (0.49) | LOXL2GAAPKMF2PNMT | |
| SCHEMBL6683148 | 0.77 | CYP2A6 (0.58) | LOXL2GAAPKMCYP2A6 | |
| SCHEMBL29673249 | 0.77 | CYP2A6 (0.58) | LOXL2GAAPKMCYP2A6 | |
| SCHEMBL7246369 | 0.75 | PPARG (0.61) | GAAFFAR1CA2SIRT1 | |
| SCHEMBL2998373 | 0.75 | FFAR1 (0.45) | LOXL2GAAPKMLOXLOXL3 | |
| SCHEMBL12803354 | 0.74 | LOXL2 (0.50) | LOXL2GAAPKMF2CYP2A6 | |
| SCHEMBL12958646 | 0.74 | LOXL2 (0.50) | LOXL2GAAPKMF2CYP2A6 | |
| Hydrochloric Acid SCHEMBL1111607 | 0.73 | GAA (0.46) | LOXL2GAAPKMF2CYP2A6 | |
| SCHEMBL1111547 | 0.73 | GAA (0.46) | LOXL2GAAPKMF2CYP2A6 | |
| SCHEMBL21214072 | 0.73 | GAA (0.42) | LOXL2GAAPKMF2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112823157-B | Spirochroman derivatives | 吉瑞工厂 | 2024-08-09 | — | — | CN | disclosed |