Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.60 |
| ▸ | IKZF2 | Q9UKS7 | 13/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20936139 | 1.00 | CRBN (0.60) | CRBNIKZF2 | |
| Hydrochloric Acid SCHEMBL20774920 | 0.99 | CRBN (0.59) | CRBNIKZF2 | |
| Hydrochloric Acid SCHEMBL30477333 | 0.99 | CRBN (0.59) | CRBNIKZF2 | |
| SCHEMBL31158016 | 0.88 | CRBN (0.60) | CRBNIKZF2 | |
| SCHEMBL25620141 | 0.84 | CRBN (0.41) | CRBNIKZF2 | |
| SCHEMBL24319424 | 0.84 | CRBN (0.66) | CRBNIKZF2 | |
| SCHEMBL21982392 | 0.84 | CRBN (0.66) | CRBNIKZF2 | |
| SCHEMBL20046087 | 0.84 | CRBN (0.66) | CRBNIKZF2 | |
| SCHEMBL29367078 | 0.84 | CRBN (0.66) | CRBNIKZF2 | |
| SCHEMBL24789380 | 0.83 | CRBN (0.57) | CRBNIKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240384007-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION | NOVARTIS AG (CH) | 2024-11-21 | — | — | US | disclosed |
| US-11999802-B2 | Compositions and methods for selective protein degradation | NOVARTIS AG (CH) | 2024-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240384007-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION | CRBN, RPS27A, COPB1 | CRBN 1/4885IKZF2 336/4885 |
| US-11999802-B2 | Compositions and methods for selective protein degradation | CRBN, RPS27A, COPB1 | CRBN 1/4885IKZF2 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.