Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242780 | 1.00 | KDM4E (0.51) | KDM4EL3MBTL1MAPTNPSR1MEN1 | |
| SCHEMBL25674716 | 0.83 | KDM4E (0.48) | KDM4EL3MBTL1MEN1MAPK1KMT2A | |
| SCHEMBL31188678 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1MEN1MAPK1KMT2A | |
| SCHEMBL30345053 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1MAPTMEN1MAPK1 | |
| SCHEMBL25717389 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1MAPTMEN1MAPK1 | |
| SCHEMBL30336602 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1MAPTMEN1MAPK1 | |
| SCHEMBL25650812 | 0.81 | KDM4E (0.46) | KDM4EL3MBTL1MAPTNPSR1MEN1 | |
| SCHEMBL16039856 | 0.79 | TP53 (0.49) | KDM4EL3MBTL1MAPTNPSR1MEN1 | |
| SCHEMBL25674355 | 0.78 | ALDH1A1 (0.42) | KDM4EMAPTMEN1MAPK1KMT2A | |
| SCHEMBL2807768 | 0.75 | KDM4E (0.47) | KDM4EL3MBTL1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118434726-A | 1H-pyrazol-3-amine derivatives having a bicyclic skeleton | 住友制药株式会社 | 2024-08-02 | — | — | CN | disclosed |