Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056923 | 0.94 | TDP1 (0.54) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL13451785 | 0.93 | TDP1 (0.57) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL31024468 | 0.91 | MAOA (0.50) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL14680159 | 0.91 | TDP1 (0.59) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL29549866 | 0.91 | TDP1 (0.59) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL31021600 | 0.87 | TDP1 (0.48) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL31021588 | 0.86 | TDP1 (0.50) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL1143295 | 0.85 | TDP1 (0.49) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL18074376 | 0.83 | TDP1 (0.72) | MAOAMAOBTDP1CA12CA1 | |
| SCHEMBL31021612 | 0.82 | TDP1 (0.44) | MAOAMAOBTDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024183821-A1 | IONIZABLE LIPID MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海吉量医药工程有限公司 | 2024-09-12 | — | — | WO | disclosed |