Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 18/20 | 0.67 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614672 | 0.95 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL24421502 | 0.95 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL31333758 | 0.94 | IKZF2 (0.64) | IKZF2IKZF1 | |
| SCHEMBL30822485 | 0.94 | IKZF2 (0.58) | IKZF2IKZF1CRBN | |
| SCHEMBL30822480 | 0.94 | IKZF2 (0.58) | IKZF2IKZF1CRBN | |
| SCHEMBL31025890 | 0.94 | IKZF2 (0.70) | IKZF2IKZF1CRBN | |
| SCHEMBL29583366 | 0.92 | IKZF2 (0.63) | IKZF2IKZF1CRBN | |
| SCHEMBL20046085 | 0.92 | IKZF2 (0.63) | IKZF2IKZF1CRBN | |
| SCHEMBL24572309 | 0.91 | IKZF2 (0.57) | IKZF2IKZF1CRBN | |
| SCHEMBL31736849 | 0.90 | IKZF2 (0.59) | IKZF2IKZF1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024162746-A1 | INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF | 한국화학연구원 | 2024-08-08 | — | — | WO | disclosed |