SCHEMBL29614672

SCHEMBL29614672

CC(C)(C)OC(=O)N1CCC(N2CCC(c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)C1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IKZF2 Q9UKS7 18/20 0.65
IKZF1 Q13422 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24421502 1.00 IKZF2 (0.65) IKZF2IKZF1
SCHEMBL31333758 0.95 IKZF2 (0.64) IKZF2IKZF1
SCHEMBL31025883 0.95 IKZF2 (0.67) IKZF2IKZF1
SCHEMBL31025890 0.95 IKZF2 (0.70) IKZF2IKZF1
SCHEMBL31737024 0.92 IKZF2 (0.59) IKZF2IKZF1
SCHEMBL31736849 0.92 IKZF2 (0.59) IKZF2IKZF1
SCHEMBL31736792 0.92 IKZF2 (0.59) IKZF2IKZF1
SCHEMBL31736513 0.92 IKZF2 (0.59) IKZF2IKZF1
SCHEMBL31025879 0.92 IKZF2 (0.59) IKZF2IKZF1
SCHEMBL29583366 0.92 IKZF2 (0.63) IKZF2IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4240743-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE Prelude Therapeutics, Incorporated (US) 2023-09-13 EP disclosed
WO-2022099117-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE PRELUDE THERAPEUTICS INCORPORATED (US) 2022-05-12 WO disclosed