SCHEMBL31025926

SCHEMBL31025926

O=C(O)c1[nH]c2cc(Cl)ccc2c1CO

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 1/20 0.72
BCL2 P10415 2/20 0.57
MCL1 Q07820 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9187231 0.86 GPR17 (0.74) GPR17
SCHEMBL15622821 0.85 GPR17 (0.73) GPR17BCL2MCL1
SCHEMBL9449473 0.85 GPR17 (0.77) GPR17BCL2MCL1
SCHEMBL3239036 0.84 GPR17 (1.00) GPR17
SCHEMBL9449366 0.84 GPR17 (0.71) GPR17BCL2MCL1
SCHEMBL31025882 0.82 GPR17 (0.65) GPR17BCL2MCL1
SCHEMBL9186049 0.81 GPR17 (0.85) GPR17BCL2MCL1
SCHEMBL9188204 0.80 GPR17 (0.82) GPR17BCL2MCL1
SCHEMBL8910112 0.80 GPR17 (0.61) GPR17
SCHEMBL9449344 0.79 GPR17 (0.60) GPR17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed