Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492841 | 1.00 | ACKR3 (0.40) | ACKR3PTPN2EGLN2GAAALDH1A1 | |
| SCHEMBL25810667 | 0.92 | ACKR3 (0.41) | ACKR3PTPN2GAAALDH1A1LMNA | |
| SCHEMBL30492870 | 0.88 | ACKR3 (0.41) | ACKR3EGLN2ALDH1A1LMNACYP2C9 | |
| SCHEMBL25810786 | 0.88 | ACKR3 (0.41) | ACKR3EGLN2ALDH1A1LMNACYP2C9 | |
| SCHEMBL25260268 | 0.87 | MAPT (0.49) | ACKR3GAAALDH1A1LMNAMEN1 | |
| SCHEMBL30492859 | 0.87 | MAPT (0.49) | ACKR3GAAALDH1A1LMNAMEN1 | |
| SCHEMBL31025974 | 0.83 | PTPN2 (0.40) | PTPN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL25296886 | 0.83 | PTPN2 (0.40) | PTPN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL25301130 | 0.82 | PTPN2 (0.42) | PTPN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL30492853 | 0.82 | PTPN2 (0.42) | PTPN2GAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488951-A | Fused bicyclic heteroaryl amide compounds as inhibitors of protein aggregation | 上海京新生物医药有限公司 | 2024-08-13 | — | — | CN | disclosed |