Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492870 | 1.00 | ACKR3 (0.41) | ACKR3EGLN2CYP2C9NAMPTRPA1 | |
| SCHEMBL25810669 | 0.91 | SCD5 (0.43) | ACKR3CYP2C9NAMPTALDH1A1LMNA | |
| SCHEMBL31025966 | 0.88 | ACKR3 (0.40) | ACKR3EGLN2CYP2C9NAMPTALDH1A1 | |
| SCHEMBL30492841 | 0.88 | ACKR3 (0.40) | ACKR3EGLN2CYP2C9NAMPTALDH1A1 | |
| SCHEMBL25252167 | 0.86 | MAPT (0.53) | ACKR3CYP2C9NAMPTALDH1A1LMNA | |
| SCHEMBL30492816 | 0.86 | MAPT (0.53) | ACKR3CYP2C9NAMPTALDH1A1LMNA | |
| SCHEMBL25810667 | 0.79 | ACKR3 (0.41) | ACKR3CYP2C9NAMPTALDH1A1LMNA | |
| SCHEMBL25253830 | 0.78 | BCL2L1 (0.42) | RPA1BCL2L1NR1H4 | |
| SCHEMBL25297616 | 0.78 | BCL2L1 (0.46) | RPA1BCL2L1NR1H4 | |
| SCHEMBL21877295 | 0.76 | PARP1 (0.45) | EGLN2ALDH1A1LMNAMAPTPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |