Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492856 | 1.00 | LGMN (0.51) | LGMNSIRT2SIRT1LMNAMEN1 | |
| SCHEMBL31026002 | 0.88 | KDM4E (0.47) | LMNAMAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL30492912 | 0.88 | KDM4E (0.47) | LMNAMAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL25809773 | 0.87 | HRH4 (0.43) | LGMNLMNAMAPTKDM4EL3MBTL1 | |
| SCHEMBL17858381 | 0.87 | MAPT (0.49) | LGMNLMNAMEN1KMT2ALRRK2 | |
| SCHEMBL30492874 | 0.86 | CHRNA7 (0.43) | LGMNLMNAMEN1KMT2AMAPT | |
| SCHEMBL25810428 | 0.86 | CHRNA7 (0.43) | LGMNLMNAMEN1KMT2AMAPT | |
| SCHEMBL30492882 | 0.86 | CHRNA7 (0.40) | LGMNSIRT2SIRT1LMNACSNK1D | |
| SCHEMBL25298855 | 0.85 | CHRNA7 (0.43) | LGMNLMNAMEN1KMT2AMAPT | |
| SCHEMBL31025994 | 0.85 | CHRNA7 (0.43) | LGMNLMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488951-A | Fused bicyclic heteroaryl amide compounds as inhibitors of protein aggregation | 上海京新生物医药有限公司 | 2024-08-13 | — | — | CN | disclosed |