Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGDS | O60760 | 4/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038770 | 0.83 | MMP13 (0.60) | HPGDSMMP13KMT2AALDH1A1HDAC2 | |
| SCHEMBL12266355 | 0.81 | MMP13 (0.59) | SMN1; SMN2HPGDSMMP13HPGDKMT2A | |
| SCHEMBL12749843 | 0.77 | EGFR (0.52) | HPGDSMMP13KMT2AL3MBTL1EGFR | |
| SCHEMBL16126516 | 0.75 | POLB (0.55) | SMN1; SMN2MMP13HPGDKMT2AALDH1A1 | |
| SCHEMBL11650826 | 0.75 | HPGD (0.55) | SMN1; SMN2HPGDSMMP13HPGDALDH1A1 | |
| SCHEMBL22011494 | 0.75 | NPC1 (0.53) | SMN1; SMN2 | |
| SCHEMBL21962000 | 0.75 | NPC1 (0.56) | SMN1; SMN2HPGDKMT2AALDH1A1 | |
| SCHEMBL14659580 | 0.75 | ATR (0.53) | SMN1; SMN2KMT2AALDH1A1HDAC2HDAC8 | |
| SCHEMBL8042301 | 0.75 | HDAC6 (0.77) | SMN1; SMN2HPGDKMT2AALDH1A1HDAC2 | |
| SCHEMBL17697619 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDSKMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118439994-A | Preparation method of 2-pyridine carboxamide compound | 江阴迈康升华医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |