Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 9/20 | 0.43 |
| ▸ | MGAM | O43451 | 6/20 | 0.43 |
| ▸ | SI | P14410 | 6/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026330 | 0.93 | MEN1 (0.55) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026331 | 0.90 | MEN1 (0.59) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026321 | 0.84 | MEN1 (0.55) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026318 | 0.83 | MEN1 (0.77) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL7012422 | 0.83 | MEN1 (0.77) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026323 | 0.81 | MEN1 (0.77) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL10755594 | 0.80 | GPR84 (0.44) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL2518589 | 0.79 | MEN1 (0.55) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026329 | 0.78 | MAPT (0.53) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026317 | 0.74 | MEN1 (0.54) | MEN1KMT2APOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420514-A | Method for synthesizing 3- (2-nitro-1-aryl) -1H-indole derivative by using cyclopentadienyl titanium/Bronsted acid in synergistic catalysis mode | 宁夏师范学院 | 2024-08-02 | — | — | CN | disclosed |