Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026515 | 0.92 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30925925 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL24994395 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL24993627 | 0.83 | KMT2A (0.54) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29214905 | 0.83 | KMT2A (0.54) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL24994392 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL24993399 | 0.82 | SCN2A (0.58) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29214960 | 0.82 | SCN2A (0.58) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31026528 | 0.81 | KMT2A (0.56) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL24993638 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4660183-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING PHENOLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2025-12-10 | — | — | EP | claimed |
| WO-2024159286-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING PHENOLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2024-08-08 | — | — | WO | claimed |
| EP-4660183-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING PHENOLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024159286-A1 | NAV1.7- AND/OR NAV1.8-INHIBITING PHENOLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | EUROFARMA LABORATÓRIOS S.A. (BR) | 2024-08-08 | — | — | WO | disclosed |