Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1330970 | 1.00 | TDP1 (0.67) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL3392091 | 0.89 | KDM4C (0.62) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL30923484 | 0.89 | KDM4C (0.62) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL11870062 | 0.89 | KDM4C (0.62) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11417342 | 0.87 | KDM4C (0.60) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL15550884 | 0.85 | SIRT3 (0.60) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL29741235 | 0.84 | TDP1 (0.59) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL22190223 | 0.84 | TDP1 (0.55) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL29740415 | 0.84 | TDP1 (0.59) | TDP1SIRT3KDM4EKDM4CALDH1A1 | |
| SCHEMBL29374289 | 0.84 | SIRT3 (0.55) | TDP1SIRT3KDM4EKDM4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483387-B | Method for synthesizing nicotinamide amide derivative by one-pot method | 广东医科大学 | 2023-01-31 | — | — | CN | claimed |
| CN-115611855-A | Nicotinamide type compound and application thereof in preparation of weight-losing medicine | 西北大学 | 2023-01-17 | — | — | CN | claimed |
| CN-110483391-B | Five-component synthesis method of nicotinamide amide derivative | 广东医科大学 | 2022-09-30 | — | — | CN | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| EP-3965738-B1 | METHOD FOR PRODUCTION OF LIPOSOMES | UNIV DO MINHO (PT) | 2025-08-06 | — | — | EP | disclosed |
| US-20230172854-A1 | A SOLID CO-AMORPHOUS DISPERSION OF VALSARTAN, A METHOD FOR SYNTHETIZING THE SAME AND A MEDICAL USE OF THE DISPERSION | UNIV HUMANISTYCZNO PRZYRODNICZY IM JANA DLUGOSZA W CZESTOCHOWIE (PL) | 2023-06-08 | — | — | US | disclosed |
| CN-110483387-B | Method for synthesizing nicotinamide amide derivative by one-pot method | 广东医科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-110483387-B | Method for synthesizing nicotinamide amide derivative by one-pot method | 广东医科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-110483387-B | Method for synthesizing nicotinamide amide derivative by one-pot method | 广东医科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115611855-A | Nicotinamide type compound and application thereof in preparation of weight-losing medicine | 西北大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-110483391-B | Five-component synthesis method of nicotinamide amide derivative | 广东医科大学 | 2022-09-30 | — | — | CN | disclosed |
| US-4313945-A | 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping | CIBA-GEIGY CORPORATION (US) | 1982-02-02 | — | — | US | disclosed |
| US-3960877-A | PLANT GROWTH REGULATOR, WEED KILLER DEFOLIATING AGENTS | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
| US-3960877-A | PLANT GROWTH REGULATOR, WEED KILLER DEFOLIATING AGENTS | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
| US-3947442-A | Method for producing heterocyclic acid anhydrides and pyrimidinediones | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3947442-A | Method for producing heterocyclic acid anhydrides and pyrimidinediones | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3947416-A | Azaisatoic anhydrides | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3947416-A | Azaisatoic anhydrides | THE SHERWIN-WILLIAMS COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3887550-A | Method for producing heterocyclic acid anhydrides | GLENFED FINANCIAL CORPORATION | 1975-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172854-A1 | A SOLID CO-AMORPHOUS DISPERSION OF VALSARTAN, A METHOD FOR SYNTHETIZING THE SAME AND A MEDICAL USE OF THE DISPERSION | ACE2, ACE, AGTR2 | TDP1 3368/4885SIRT3 24/4885KDM4E 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.