Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099311 | 0.89 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL13254961 | 0.80 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL3102248 | 0.72 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3102430 | 0.71 | CSNK1D (0.47) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL3094572 | 0.70 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL3102530 | 0.70 | CSNK1D (0.51) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL3100712 | 0.68 | CSNK1D (0.48) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL3100701 | 0.68 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL3091756 | 0.68 | CSNK1D (0.47) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL3102415 | 0.68 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273775-A1 | FUNGICIDAL BICYCLIC PYRAZOLES | CYP1B1, CBR1, CYP1A1 | MAPK14 3609/4885MAPK13 3354/4885MAPK12 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.