Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | CBFB | Q13951 | 3/20 | 0.39 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 7/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170829 | 0.79 | EGLN1 (0.43) | CBFBSSTR5EGLN1DHODHPTGDR2 | |
| SCHEMBL24075055 | 0.76 | KDM4E (0.56) | METAP1CBFBSRPK2SRPK1PDE10A | |
| SCHEMBL21705589 | 0.71 | METAP1 (0.62) | METAP1CBFBPDE10AMETAP2DGAT1 | |
| SCHEMBL31063827 | 0.71 | METAP1 (0.62) | METAP1CBFBPDE10AMETAP2DGAT1 | |
| SCHEMBL8510130 | 0.67 | METAP1 (0.56) | METAP1CBFBPDE10AMETAP2 | |
| SCHEMBL28091993 | 0.66 | METAP1 (0.54) | METAP1PDE10A | |
| SCHEMBL1021801 | 0.66 | METAP1 (0.67) | METAP1METAP2 | |
| SCHEMBL30073835 | 0.66 | METAP1 (0.67) | METAP1METAP2 | |
| SCHEMBL17674149 | 0.66 | MAPT (0.56) | METAP1F2RL1 | |
| SCHEMBL17276072 | 0.65 | PNP (0.47) | SSTR5EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118936-A1 | 2-ARYLBENZIMIDAZOLE COMPOUNDS FOR THE TREATMENT OF HEMOGLOBINOPATHIES | TRANQUIS THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |