SCHEMBL1021801

SCHEMBL1021801

c1ccc2[nH]c(-c3nccs3)nc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 3/20 0.67
RAB9A P51151 8/20 0.61
NPC1 O15118 7/20 0.61
KDM4E B2RXH2 7/20 0.61
SMN1; SMN2 Q16637 6/20 0.61
ALDH1A1 P00352 6/20 0.61
HPGD P15428 5/20 0.61
HSD17B10 Q99714 5/20 0.61
METAP2 P50579 3/20 0.58
PKM P14618 2/20 0.58
LMNA P02545 1/20 0.58
MTOR P42345 1/20 0.58
TP53 P04637 4/20 0.58
NPSR1 Q6W5P4 3/20 0.58
ABCB11 O95342 1/20 0.58
PKN1 Q16512 1/20 0.56
PKN2 Q16513 1/20 0.56
ALOX15 P16050 3/20 0.54
MAPK1 P28482 3/20 0.54
CYP3A4 P08684 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30073835 1.00 METAP1 (0.67) METAP1RAB9ANPC1KDM4ESMN1; SMN2
Zinc Ion SCHEMBL8449508 0.93 METAP1 (0.58) METAP1RAB9ANPC1KDM4ESMN1; SMN2
SCHEMBL27926818 0.78 HPGD (0.65) RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL4367711 0.78 GAA (0.63) METAP1RAB9ANPC1KDM4ESMN1; SMN2
SCHEMBL3538845 0.78 GSK3B (0.55) METAP1RAB9ANPC1KDM4ESMN1; SMN2
SCHEMBL30659968 0.77 NPC1 (0.69) METAP1RAB9ANPC1KDM4ESMN1; SMN2
SCHEMBL1535707 0.77 NPC1 (0.69) METAP1RAB9ANPC1KDM4ESMN1; SMN2
SCHEMBL30659969 0.77 NPC1 (0.69) METAP1RAB9ANPC1KDM4ESMN1; SMN2
SCHEMBL2249384 0.76 ALDH1A1 (1.00) RAB9ANPC1KDM4ESMN1; SMN2ALDH1A1
SCHEMBL30561047 0.75 NPC1 (1.00) METAP1RAB9ANPC1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11297964-B1 Antimicrobial roll-up floor cover MCTECH GROUP, INC. (US) 2022-04-12 US claimed
US-20220087462-A1 Antimicrobial Roll-Up Floor Cover MCTECH GROUP, INC. 2022-03-24 US claimed
WO-2021128102-A1 FLAME-RETARDANT WOOD-PLASTIC SURFACE LAYER COMPOSITE, AND METHOD FOR PREPARING WOOD-PLASTIC COMPOSITE MATERIAL HAVING FLAME-RETARDANT WOOD-PLASTIC SURFACE COMPOSITE 宁波禾隆新材料股份有限公司 2021-07-01 WO claimed
CN-111116613-B Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof 湘潭大学 2021-04-23 CN claimed
CN-111471390-A Antibacterial and grease-resistant coating for plastic surface and preparation method thereof 东莞市凯成环保科技有限公司 2020-07-31 CN claimed
CN-111116613-A Polysubstituted benzimidazole thiazole and derivative and synthesis method thereof 湘潭大学 2020-05-08 CN claimed
CN-111019219-A Flame-retardant wood-plastic surface layer composite and preparation method of wood-plastic composite material with flame-retardant wood-plastic surface layer composite 宁波禾隆新材料股份有限公司 2020-04-17 CN claimed
EP-3387181-B1 WINDOW BLIND FABRIC COATED WITH POLLEN DENATURATION COATING COMPOSITON LOUVER LITE LTD (GB) 2020-01-29 EP claimed
US-20180363238-A1 Pollen Denaturation Coating Composition for Fabrics LOUVER-LITE LIMITED (GB) 2018-12-20 US claimed
EP-3387181-A1 POLLEN DENATU RATION COATING COMPOSITON FOR FABRICS Louver-Lite Limited (GB) 2018-10-17 EP claimed
EP-0963291-A4 DISCOLORATION PREVENTION IN PYRITHIONE-CONTAINING COATING COMPOSITIONS ARCH CHEM INC (US) 2000-05-17 EP claimed
EP-0963291-A1 DISCOLORATION PREVENTION IN PYRITHIONE-CONTAINING COATING COMPOSITIONS Arch Chemicals, Inc. (US) 1999-12-15 EP claimed
JP-2986218-B2 1999-12-06 JP claimed
US-5939203-A ZINC OXIDE COMPOUNDS; PAINTS; MILDEW AND RADIATION RESISTANCE ARCH CHEMICALS, INC. (US) 1999-08-17 US claimed
US-5869172-A POROUS WEB TREATED WITH PARTIALLY CURED SHEAR THINNABLE THIXOTROPIC POLYMER AND MODIFIERS SELECTIVELY POSITIONED WITHIN WEB NEXTEC APPLICATIONS, INC. (US) 1999-02-09 US claimed
WO-1998036904-B1 DISCOLORATION PREVENTION IN PYRITHIONE-CONTAINING COATING COMPOSITIONS 1998-10-01 WO claimed
WO-1998036904-A1 DISCOLORATION PREVENTION IN PYRITHIONE-CONTAINING COATING COMPOSITIONS ARCH CHEMICALS, INC. (US) 1998-08-27 WO claimed
EP-0826082-A2 INTERNALLY-COATED POROUS WEBS WITH CONTROLLED POSITIONING OF MODIFIERS THEREIN Nextec Applications, Inc. (US) 1998-03-04 EP claimed
WO-1996036758-A2 INTERNALLY-COATED POROUS WEBS WITH CONTROLLED POSITIONING OF MODIFIERS THEREIN NEXTEC APPLICATIONS, INC. (US) 1996-11-21 WO claimed
EP-0190036-A2 Fungicidal pyridine derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-08-06 EP claimed