Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556997 | 0.82 | JAK2 (0.36) | HPGDMAPTPOLBGAATDP1 | |
| SCHEMBL31028063 | 0.78 | CTSL (0.42) | MEN1ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL3722023 | 0.74 | PARP10 (0.40) | MAPTPARP1PARP10PARP11 | |
| SCHEMBL31028052 | 0.74 | MAPT (0.33) | MAPTPARP1 | |
| SCHEMBL3722025 | 0.74 | PARP10 (0.40) | MAPTPARP1PARP10PARP11 | |
| SCHEMBL624115 | 0.71 | CYP19A1 (0.47) | ALDH1A1MAPTNPC1SMN1; SMN2POLB | |
| SCHEMBL5712020 | 0.71 | CYP19A1 (0.47) | ALDH1A1MAPTNPC1SMN1; SMN2POLB | |
| SCHEMBL15010704 | 0.71 | CYP19A1 (0.47) | ALDH1A1MAPTNPC1SMN1; SMN2POLB | |
| SCHEMBL14577148 | 0.69 | POLB (0.37) | HPGDMAPTPOLBTDP1LMNA | |
| SCHEMBL14577147 | 0.69 | POLB (0.37) | HPGDMAPTPOLBTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546047-B | Preparation method of cyclic chiral nitrile compound and application of cyclic chiral nitrile compound in preparation of ramelteon | 北京师范大学 | 2025-02-07 | — | — | CN | disclosed |
| CN-118546047-A | Preparation method of cyclic chiral nitrile compound and application of cyclic chiral nitrile compound in preparation of ramelteon | 北京师范大学 | 2024-08-27 | — | — | CN | disclosed |