SCHEMBL31028151

SCHEMBL31028151

O=C(O)c1ccc(CNC(=O)c2cc(-c3cncnc3)ccc2Oc2ccc(F)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 6/20 0.74
PTGER2 P43116 3/20 0.74
CYP3A4 P08684 1/20 0.49
MAPK14 Q16539 1/20 0.49
PPARD Q03181 2/20 0.47
PPARA Q07869 2/20 0.47
PPARG P37231 1/20 0.47
MAPT P10636 2/20 0.45
THRB P10828 1/20 0.45
SCN9A Q15858 1/20 0.44
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
NR1H4 Q96RI1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22319376 1.00 PTGER4 (0.74) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL22319379 0.91 PTGER4 (0.85) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL31028174 0.91 PTGER4 (0.85) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL22319370 0.91 PTGER4 (0.60) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL22319380 0.90 PTGER4 (0.70) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL31028146 0.90 PTGER4 (0.70) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL22319348 0.89 PTGER4 (0.76) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL31028149 0.89 PTGER4 (0.76) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL22319364 0.88 PTGER4 (0.80) PTGER4PTGER2CYP3A4MAPK14PPARD
SCHEMBL22319351 0.88 PTGER4 (0.80) PTGER4PTGER2PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646299-B Novel N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE 2) receptor modulators 梅迪比奥法尔玛公司 2024-07-26 CN claimed
CN-113646299-B Novel N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE 2) receptor modulators 梅迪比奥法尔玛公司 2024-07-26 CN disclosed