Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ERN1 | O75460 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19269479 | 0.92 | TSHR (0.41) | PRKDCTSHRCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15713801 | 0.82 | ERN1 (0.40) | PRKDCTSHRALDH1A1ERN1LMNA | |
| SCHEMBL3204262 | 0.82 | TSHR (0.48) | TSHRCYP3A4MAPK1ALDH1A1ERN1 | |
| SCHEMBL3847770 | 0.80 | ALDH1A1 (0.46) | PRKDCTSHRCYP3A4ALDH1A1ERN1 | |
| SCHEMBL29447325 | 0.80 | ALDH1A1 (0.46) | PRKDCTSHRCYP3A4ALDH1A1ERN1 | |
| SCHEMBL8444257 | 0.80 | TSHR (0.52) | TSHRCYP3A4MAPK1ALDH1A1ERN1 | |
| SCHEMBL20437528 | 0.79 | CYP3A4 (0.36) | TSHRCYP3A4MAPK1ALDH1A1TDP1 | |
| SCHEMBL15873472 | 0.77 | ERN1 (0.41) | PRKDCALDH1A1ERN1LMNA | |
| SCHEMBL31456072 | 0.76 | PRKDC (0.63) | PRKDCTSHRCYP3A4ALDH1A1ERN1 | |
| SCHEMBL15031973 | 0.76 | PRKDC (0.63) | PRKDCTSHRCYP3A4ALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662206-A1 | GSPT1 DEGRADER COMPOUNDS | Captor Therapeutics S.A. (PL) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024165577-A1 | GSPT1 DEGRADER COMPOUNDS | CAPTOR THERAPEUTICS S.A. (PL) | 2024-08-15 | — | — | WO | disclosed |