Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505552 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAHTTHPGDNPC1 | |
| SCHEMBL2480481 | 0.80 | GALR3 (0.45) | SMN1; SMN2LMNAHTTHPGDNPC1 | |
| SCHEMBL11717809 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAHTTHPGDNPC1 | |
| SCHEMBL14782611 | 0.76 | PDPK1 (0.39) | SMN1; SMN2LMNAHTTKDM4EMEN1 | |
| SCHEMBL11904205 | 0.76 | TDP1 (0.38) | SMN1; SMN2LMNAHTTHPGDNPC1 | |
| SCHEMBL20575177 | 0.75 | EGFR (0.52) | — | |
| SCHEMBL20575176 | 0.75 | EGFR (0.52) | — | |
| SCHEMBL13472315 | 0.74 | HPGD (0.39) | SMN1; SMN2LMNAHTTHPGDNPC1 | |
| SCHEMBL4665922 | 0.73 | CA1 (0.50) | SMN1; SMN2LMNAHTTHPGDNPC1 | |
| SCHEMBL10501775 | 0.71 | TDP1 (0.40) | SMN1; SMN2LMNAHTTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300133-B | Heterocyclic compound and application thereof | 深圳微芯生物科技股份有限公司 | 2024-07-30 | — | — | CN | disclosed |