Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 12/20 | 0.54 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324364 | 0.90 | SCD (0.43) | SCDSCD5KDM4EALDH1A1HPGD | |
| SCHEMBL3320588 | 0.90 | SCD (0.50) | SCDSCD5KDM4EALDH1A1HPGD | |
| SCHEMBL3320580 | 0.90 | SCD (0.50) | SCDSCD5KDM4EALDH1A1HPGD | |
| SCHEMBL3320581 | 0.90 | SCD (0.50) | SCDSCD5KDM4EALDH1A1HPGD | |
| SCHEMBL3261795 | 0.87 | SCD (0.46) | SCDSCD5KDM4EALDH1A1HPGD | |
| SCHEMBL3233175 | 0.87 | SCD (0.45) | SCDSCD5KDM4EALDH1A1HPGD | |
| SCHEMBL3319925 | 0.87 | SCD (0.46) | SCDSCD5KDM4EALDH1A1HPGD | |
| SCHEMBL473052 | 0.86 | SCD (0.73) | SCDSCD5 | |
| SCHEMBL3320435 | 0.85 | SCD (0.74) | SCDSCD5 | |
| SCHEMBL13332472 | 0.83 | SCD (0.61) | SCDSCD5ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-05-13 | — | — | US | disclosed |
| EP-2148878-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Frosst Canada Ltd. (CA) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008128335-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, ACSL6 | SCD 1/4885SCD5 2/4885KDM4E 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.