Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020973 | 1.00 | LMNA (0.48) | LMNAMEN1KMT2AHRH3HPGD | |
| SCHEMBL8655896 | 0.86 | HRH3 (0.48) | LMNAMEN1KMT2AHRH3TAAR1 | |
| SCHEMBL30486831 | 0.84 | KMT2A (0.33) | LMNAMEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL11503834 | 0.78 | LMNA (0.46) | LMNAMEN1KMT2AHRH3HPGD | |
| SCHEMBL11293433 | 0.76 | LMNA (0.45) | LMNAMEN1KMT2AHRH3HPGD | |
| SCHEMBL6248108 | 0.75 | LMNA (0.38) | LMNAKMT2AALDH1A1 | |
| SCHEMBL7446651 | 0.74 | CYP2D6 (0.50) | LMNAMEN1KMT2AHRH3HPGD | |
| SCHEMBL9472909 | 0.73 | EPHX1 (0.45) | SIGMAR1 | |
| SCHEMBL28169030 | 0.73 | DPP4 (0.43) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28550991 | 0.72 | SMN1; SMN2 (0.47) | LMNAMEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440267-A | Chiral covalent organic framework compound and preparation method thereof, rhodium-loaded metal compound and application thereof, and preparation method of intermediate | 河北科技大学 | 2024-08-06 | — | — | CN | claimed |
| CN-118440267-A | Chiral covalent organic framework compound and preparation method thereof, rhodium-loaded metal compound and application thereof, and preparation method of intermediate | 河北科技大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-118440267-A | Chiral covalent organic framework compound and preparation method thereof, rhodium-loaded metal compound and application thereof, and preparation method of intermediate | 河北科技大学 | 2024-08-06 | — | — | CN | disclosed |