Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.78 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.78 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.78 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.78 |
| ▸ | RAF1 | P04049 | 5/20 | 0.78 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.78 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | GCGR | P47871 | 2/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6449249 | 0.89 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL30713384 | 0.86 | MAPK13 (0.60) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL31029951 | 0.85 | MAPK13 (0.89) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL2649073 | 0.85 | MAPK14 (0.76) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL14514175 | 0.84 | PTPN1 (0.73) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL20445314 | 0.84 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| Hydrochloric Acid SCHEMBL23736216 | 0.83 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| Hydrochloric Acid SCHEMBL31679086 | 0.83 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL6469211 | 0.82 | MAPK14 (0.81) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL6469918 | 0.81 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440005-A | Trisubstituted arylamine imidazole compound and preparation method and application thereof | 华中科技大学 | 2024-08-06 | — | — | CN | disclosed |