Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 13/20 | 0.89 |
| ▸ | MAPK12 | P53778 | 13/20 | 0.89 |
| ▸ | MAPK11 | Q15759 | 13/20 | 0.89 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.89 |
| ▸ | RAF1 | P04049 | 7/20 | 0.89 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.69 |
| ▸ | GCGR | P47871 | 6/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | BRAF | P15056 | 2/20 | 0.61 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464525 | 0.94 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL67984 | 0.88 | MAPK13 (0.89) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL5074753 | 0.87 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL6469444 | 0.86 | MAPK13 (0.68) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL31029950 | 0.85 | MAPK14 (0.78) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL16667652 | 0.85 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| Benzene SCHEMBL28852698 | 0.85 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL104130 | 0.85 | MAPK13 (0.82) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| SCHEMBL23437865 | 0.83 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14RAF1 | |
| Methane SCHEMBL3278320 | 0.83 | MAPK13 (0.79) | MAPK13MAPK12MAPK11MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440005-A | Trisubstituted arylamine imidazole compound and preparation method and application thereof | 华中科技大学 | 2024-08-06 | — | — | CN | disclosed |