Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.44 |
| ▸ | NPY1R | P25929 | 8/20 | 0.44 |
| ▸ | NPY2R | P49146 | 6/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031102 | 0.92 | RXFP1 (0.47) | NPY4RNPY1RNPY2RNPY5RRXFP1 | |
| SCHEMBL31031101 | 0.92 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL31031104 | 0.91 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RSIRT6 | |
| SCHEMBL31031099 | 0.90 | RXFP1 (0.51) | NPY4RNPY1RNPY2RNPY5RRXFP1 | |
| SCHEMBL31440867 | 0.88 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31031105 | 0.85 | RXFP1 (0.45) | NPY4RNPY1RNPY2RNPY5RRXFP1 | |
| SCHEMBL29355280 | 0.82 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL24049263 | 0.81 | NPY4R (0.56) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31031107 | 0.81 | RXFP1 (0.46) | NPY4RNPY1RNPY2RNPY5RRXFP1 | |
| SCHEMBL31433331 | 0.80 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146308-A | Cyclic peptides for treating gastric cancer and pharmaceutical composition thereof | 中国科学院分子细胞科学卓越创新中心 | 2024-06-07 | — | — | CN | claimed |
| CN-118146308-A | Cyclic peptides for treating gastric cancer and pharmaceutical composition thereof | 中国科学院分子细胞科学卓越创新中心 | 2024-06-07 | — | — | CN | disclosed |