Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 14/20 | 0.44 |
| ▸ | NPY1R | P25929 | 9/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.44 |
| ▸ | NPY2R | P49146 | 6/20 | 0.44 |
| ▸ | TFPI | P10646 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031100 | 0.92 | NPY4R (0.44) | RXFP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31031099 | 0.90 | RXFP1 (0.51) | RXFP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31440867 | 0.88 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL30148948 | 0.87 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2REGFR | |
| SCHEMBL31628012 | 0.85 | NPY4R (0.54) | RXFP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31031101 | 0.84 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RSIRT6 | |
| SCHEMBL31031104 | 0.83 | NPY4R (0.44) | NPY4RNPY1RNPY5RNPY2RSIRT6 | |
| SCHEMBL31433331 | 0.82 | NPY4R (0.48) | NPY4RNPY1RNPY5RNPY2RTFPI | |
| SCHEMBL10168777 | 0.82 | RXFP1 (0.53) | RXFP1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL10168328 | 0.82 | RXFP1 (0.53) | RXFP1NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146308-A | Cyclic peptides for treating gastric cancer and pharmaceutical composition thereof | 中国科学院分子细胞科学卓越创新中心 | 2024-06-07 | — | — | CN | claimed |
| CN-118146308-A | Cyclic peptides for treating gastric cancer and pharmaceutical composition thereof | 中国科学院分子细胞科学卓越创新中心 | 2024-06-07 | — | — | CN | disclosed |