Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311469 | 0.73 | KDM4E (0.38) | GAASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL15430407 | 0.67 | GAA (0.35) | GAASMN1; SMN2ADORA3ALDH1A1MAPT | |
| SCHEMBL1147259 | 0.67 | EPHX2 (0.33) | GAASMN1; SMN2ADORA3ALDH1A1MAPT | |
| SCHEMBL8189070 | 0.66 | GAA (0.34) | GAASMN1; SMN2ADORA3ALDH1A1MAPT | |
| SCHEMBL2854510 | 0.64 | P2RX4 (0.35) | — | |
| SCHEMBL5740741 | 0.64 | ADORA3 (0.35) | GAASMN1; SMN2ADORA3ALDH1A1MAPT | |
| SCHEMBL6312295 | 0.62 | KDM4E (0.42) | SMN1; SMN2ADORA3ALDH1A1MAPTKDM4E | |
| SCHEMBL2057181 | 0.62 | HPGD (0.37) | — | |
| SCHEMBL7286031 | 0.62 | DNMT1 (0.40) | — | |
| SCHEMBL6313569 | 0.62 | KMT2A (0.42) | GAASMN1; SMN2ADORA3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |