Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPM1 | P06748 | 3/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031250 | 0.78 | KDM4E (0.31) | KDM4EALDH1A1GLAGAAPOLB | |
| SCHEMBL31031257 | 0.78 | ALDH1A1 (0.41) | NPM1ALKKDM4EALDH1A1GLA | |
| SCHEMBL31031251 | 0.76 | SUV39H2 (0.35) | — | |
| SCHEMBL21623397 | 0.73 | ALK (0.48) | NPM1ALKKDM4EALDH1A1GLA | |
| SCHEMBL18838772 | 0.73 | IKBKB (0.47) | NPM1ALKKDM4EALDH1A1GLA | |
| SCHEMBL12324751 | 0.73 | NPM1 (0.43) | NPM1ALKKDM4EALDH1A1GLA | |
| SCHEMBL12324172 | 0.70 | ALK (0.59) | NPM1ALKKDM4EALDH1A1GLA | |
| SCHEMBL2162685 | 0.68 | NPM1 (0.44) | NPM1ALKMAPTRAD51 | |
| SCHEMBL19714775 | 0.67 | ALDH1A1 (0.45) | NPM1ALKKDM4EALDH1A1GLA | |
| SCHEMBL974116 | 0.66 | KDM4E (0.40) | KDM4EALDH1A1GAAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658651-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | Eli Lilly and Company (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163546-A1 | NOVEL COMPOUNDS FOR TAU IMAGING | ELI LILLY AND COMPANY (US) | 2024-08-08 | — | — | WO | disclosed |