SCHEMBL31031255

SCHEMBL31031255

CC(C)(C)C(=O)Oc1cccc(I)c1OC(=O)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 16/20 0.53
LMNA P02545 2/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL364665 1.00 ELANE (0.53) ELANELMNAMAPTNPSR1MAPK1
SCHEMBL28370638 0.84 ELANE (0.62) ELANELMNAMAPTNPSR1
SCHEMBL10491994 0.83 ELANE (0.34) ELANEMAPK1
SCHEMBL29372709 0.83 ELANE (0.34) ELANEMAPK1
SCHEMBL44659 0.83 ELANE (0.34) ELANEMAPK1
SCHEMBL16868476 0.81 ELANE (0.33) ELANEMAPK1
SCHEMBL20306504 0.81 ELANE (0.54) ELANELMNAMAPTNPSR1MAPK1
SCHEMBL17938475 0.81 ELANE (0.54) ELANELMNAMAPTNPSR1MAPK1
SCHEMBL4887181 0.79 ELANE (0.53) ELANELMNAMAPTNPSR1MAPK1
SCHEMBL29607284 0.77 ELANE (0.74) ELANELMNAMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658651-A1 NOVEL COMPOUNDS FOR TAU IMAGING Eli Lilly and Company (US) 2025-12-10 EP disclosed
WO-2024163546-A1 NOVEL COMPOUNDS FOR TAU IMAGING ELI LILLY AND COMPANY (US) 2024-08-08 WO disclosed