SCHEMBL44659

SCHEMBL44659

O=C(Oc1cccc(I)c1OC(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.34
MAPK1 P28482 1/20 0.33
FABP7 O15540 1/20 0.32
FABP3 P05413 1/20 0.32
FABP5 Q01469 1/20 0.32
SLC2A1 P11166 1/20 0.32
SLC2A4 P14672 1/20 0.32
MLYCD O95822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372709 1.00 ELANE (0.34) ELANEMAPK1FABP7FABP3FABP5
SCHEMBL16868476 0.98 ELANE (0.33) ELANEMAPK1FABP7FABP3FABP5
SCHEMBL3693664 0.87 ELANE (0.39) ELANEMAPK1SLC2A1SLC2A4
SCHEMBL326468 0.84 FABP7 (0.44) ELANEMAPK1FABP7FABP3FABP5
SCHEMBL30185696 0.84 FABP7 (0.44) ELANEMAPK1FABP7FABP3FABP5
SCHEMBL31031255 0.83 ELANE (0.53) ELANEMAPK1
SCHEMBL10491994 0.83 ELANE (0.34) ELANEMAPK1FABP7FABP3FABP5
SCHEMBL364665 0.83 ELANE (0.53) ELANEMAPK1
SCHEMBL30523259 0.77 ELANE (0.35) ELANEMLYCD
SCHEMBL28404237 0.77 ELANE (0.47) ELANEMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080274-A Preparation method of functionalized polyolefin 2026-05-26 CN claimed
US-20260140444-A1 PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-05-21 US claimed
US-12590049-B2 Metal-free oxidation of pyrenes ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-03-31 US claimed
US-12372542-B2 Systems and methods for the detection of phenolic cannabinoids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-29 US claimed
CN-119977882-A Cyclohexane-fused masked 2-pyridone compound, and preparation method and application thereof 南京林业大学 2025-05-13 CN claimed
CN-119823104-A Method for directly aminating C-H bond of quinoxaline 广西大学 2025-04-15 CN claimed
EP-4496830-A1 METHOD FOR PREPARING A POLYURETHANE FOAM UNIVERSITE DE BORDEAUX (FR) 2025-01-29 EP claimed
CN-119219545-A Substituted phenol maleimide derivative and preparation method and application thereof 中国电建集团中南勘测设计研究院有限公司 2024-12-31 CN claimed
CN-119143694-A Perfluoro tertiary butyl reagent and preparation method thereof 清华大学 2024-12-17 CN claimed
CN-118184567-A Process for preparing 3-haloindole derivatives 常州工程职业技术学院 2024-06-14 CN claimed
EP-0785943-A1 SYNTHESIS OF 6-AZAANDROSTENONES GLAXO WELLCOME INC. (US) 1997-07-30 EP claimed
JP-H08508748-A 1996-09-17 JP claimed
US-5541322-A Synthesis of 6-azaandrostenones GLAXO WELLCOME INC. (US) 1996-07-30 US claimed
WO-1996016966-A1 MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME QUADRA LOGIC TECHNOLOGIES, INC. (CA) 1996-06-06 WO claimed
WO-1996011939-A1 SYNTHESIS OF 6-AZAANDROSTENONES GLAXO WELLCOME INC. (US) 1996-04-25 WO claimed
EP-0703907-A1 METHOD FOR PREPARING AN OXAZOLIDINECARBOXYLIC ACID USEFUL FOR PREPARING THERAPEUTICALLY ACTIVE TAXOIDS RHONE POULENC RORER SA (FR) 1996-04-03 EP claimed
EP-0694032-A1 METHOD FOR PREPARING $g(b)-LACTAMS Aventis Pharma S.A. (FR) 1996-01-31 EP claimed
WO-1994029284-A1 METHOD FOR PREPARING AN OXAZOLIDINECARBOXYLIC ACID USEFUL FOR PREPARING THERAPEUTICALLY ACTIVE TAXOIDS RHONE-POULENC RORER S.A. (FR) 1994-12-22 WO claimed
WO-1994024103-A1 METHOD FOR PREPARING β-LACTAMS RHONE-POULENC RORER S.A. (FR) 1994-10-27 WO claimed
EP-0097994-B1 METHOD FOR THE SOLID-PHASE SYNTHESIS OF RETRO-INVERSO POLYPEPTIDES ENICHEM S.p.A. (IT) 1987-09-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260140444-A1 PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE INO80C, INO80, NAT10 ELANE 1528/4885MAPK1 2826/4885FABP7 4683/4885
US-12590049-B2 Metal-free oxidation of pyrenes PAH, DUOX1, PPOX ELANE 2761/4885MAPK1 1077/4885FABP7 4828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.