Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | KDM5A | P29375 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.49 |
| ▸ | ASPH | Q12797 | 3/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM5C | P41229 | 1/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.49 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.49 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29272132 | 1.00 | KDM4E (0.49) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL25687802 | 0.86 | KDM4E (0.55) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL101547 | 0.82 | KDM4E (0.55) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL12258250 | 0.81 | KDM4E (0.56) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL30236990 | 0.80 | KDM4E (0.47) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL29272467 | 0.80 | KDM4E (0.47) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL29272073 | 0.79 | KDM4E (0.52) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL10872507 | 0.79 | KDM4E (0.54) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL31032261 | 0.79 | KDM4E (0.52) | KDM4EKDM5AALDH1A1KDM4CKDM5B | |
| SCHEMBL29272358 | 0.79 | GABRA1 (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |