Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31032333 | 0.99 | KMT2A (0.49) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL31032348 | 0.99 | KMT2A (0.49) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL3410479 | 0.85 | KMT2A (0.59) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL31032354 | 0.79 | MEN1 (0.40) | KMT2AMEN1KDM4EGAA | |
| SCHEMBL31032310 | 0.78 | MEN1 (0.40) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31032358 | 0.78 | MEN1 (0.40) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31032277 | 0.78 | MEN1 (0.40) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31032340 | 0.78 | MEN1 (0.40) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3409879 | 0.69 | MEN1 (0.47) | KMT2AMEN1ALDH1A1HSD17B10GLA | |
| SCHEMBL432253 | 0.69 | MEN1 (1.00) | KMT2AMEN1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287033-A1 | DEGRADERS OF TISSUE TRANSGLUTAMINASE 2 (TG2) | UNITED STATES GOVERNMENT | 2024-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287033-A1 | DEGRADERS OF TISSUE TRANSGLUTAMINASE 2 (TG2) | PSMG3, UBE2G2, UBE2L3 | KMT2A 240/4885MEN1 606/4885LMNA 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.