SCHEMBL31032974

SCHEMBL31032974

C=CC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCN(S(=O)(=O)c2cccc3ccccc23)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22895106 1.00 TGM2 (1.00) TGM2
SCHEMBL19480342 0.90 TGM2 (1.00) TGM2
SCHEMBL19463909 0.90 TGM2 (1.00) TGM2
SCHEMBL19463642 0.88 TGM2 (1.00) TGM2
SCHEMBL22895107 0.88 TGM2 (1.00) TGM2
SCHEMBL22895131 0.88 TGM2 (1.00) TGM2
SCHEMBL31032928 0.88 TGM2 (1.00) TGM2
SCHEMBL19480306 0.87 TGM2 (1.00) TGM2
SCHEMBL31033030 0.87 TGM2 (1.00) TGM2
SCHEMBL22895108 0.87 TGM2 (1.00) TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442533-B1 TG2 INHIBITOR COMPOUNDS AND USES THEREOF UNIV OTTAWA (CA) 2024-08-07 — — EP disclosed
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