Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.47 |
| ▸ | MAP2K3 | P46734 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 4/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567393 | 0.85 | KDM4E (0.44) | BCAT2KDM4EALDH1A1CASP1CYP3A4 | |
| SCHEMBL27202058 | 0.79 | IKBKB (0.49) | IKBKBCHEK2KDM4EALDH1A1CASP1 | |
| SCHEMBL30665069 | 0.78 | CA1 (0.42) | IKBKBCHEK2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL231896 | 0.76 | MKNK1 (0.56) | BCAT2MAP2K3ADORA2AIKBKBMKNK1 | |
| SCHEMBL22588702 | 0.75 | SMARCA2 (0.53) | ADORA2AHSD17B10ALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL23067311 | 0.74 | MAP2K3 (0.50) | BCAT2MAP2K3ADORA2AIKBKBMKNK1 | |
| SCHEMBL2848953 | 0.74 | ADORA2A (0.46) | BCAT2MAP2K3ADORA2AIKBKBMKNK1 | |
| Hydrochloric Acid SCHEMBL27209691 | 0.73 | SMARCA2 (0.52) | ADORA2AHSD17B10ALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL30423145 | 0.72 | ADORA2A (0.45) | BCAT2MAP2K3ADORA2AIKBKBMKNK1 | |
| SCHEMBL28929678 | 0.72 | LMNA (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4389738-A1 | SOS1 INHIBITOR AND USE THEREOF | Kanaph Therapeutics Inc. (KR) | 2024-06-26 | — | — | EP | disclosed |