Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15760097 | 0.82 | MAPK14 (0.46) | KDM4EALDH1A1NPSR1HPGDTSHR | |
| SCHEMBL9957784 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10NPSR1HPGD | |
| SCHEMBL9558550 | 0.78 | KDM4E (0.54) | KDM4EOPRM1OPRD1 | |
| SCHEMBL9650199 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10NPSR1HPGD | |
| SCHEMBL30343301 | 0.77 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10NPSR1HPGD | |
| SCHEMBL11455551 | 0.77 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10NPSR1HPGD | |
| SCHEMBL29489100 | 0.76 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10NPSR1HPGD | |
| SCHEMBL28357168 | 0.76 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10NPSR1HPGD | |
| SCHEMBL12060288 | 0.76 | KCNH2 (0.63) | — | |
| SCHEMBL5547083 | 0.75 | KMT2A (0.56) | KDM4EALDH1A1HSD17B10NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163956-A2 | SIGMA RECEPTOR LIGAND COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-08-08 | — | — | WO | disclosed |