Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23812437 | 0.90 | ALDH1A1 (0.69) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| SCHEMBL21027551 | 0.86 | ALDH1A1 (0.73) | TDP1ALDH1A1G6PDCASP7CASP6 | |
| SCHEMBL2005925 | 0.86 | ALDH1A1 (0.63) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| Benzyl Salicylate SCHEMBL15573 | 0.85 | TDP1 (1.00) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| Benzyl Salicylate SCHEMBL1871397 | 0.85 | TDP1 (1.00) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| Benzyl Salicylate SCHEMBL30184766 | 0.85 | TDP1 (1.00) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| SCHEMBL30151861 | 0.84 | TDP1 (0.78) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| SCHEMBL3790907 | 0.84 | TDP1 (0.78) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| Benzyl Salicylate SCHEMBL7199160 | 0.83 | TDP1 (0.96) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A | |
| Benzyl Salicylate SCHEMBL27731147 | 0.83 | TDP1 (0.96) | TDP1ALDH1A1SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420558-B | Zhu Gongjun acid derivative and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118420557-B | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118420558-A | Zhu Gongjun acid derivative and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118420557-A | Zhu Gongjun acid analogue, and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |