Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 6/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033433 | 0.86 | PDK2 (0.43) | PDK2MAPTBCHEACHEKDM4E | |
| SCHEMBL21163804 | 0.82 | PDK2 (0.49) | PDK2MAPTGPR119KDM4EKAT6A | |
| SCHEMBL21460898 | 0.79 | CA12 (0.56) | PDK2MAPTRAPGEF3BCHE | |
| SCHEMBL21114101 | 0.79 | PDK2 (0.48) | PDK2MAPTGPR119KDM4EKAT6A | |
| SCHEMBL18121907 | 0.78 | ATM (0.36) | PDK2MAPTHTTATMTDP1 | |
| SCHEMBL21601209 | 0.78 | PDK2 (0.57) | PDK2GPR119KDM4EKAT6AKAT5 | |
| SCHEMBL30952855 | 0.78 | RAPGEF3 (0.47) | MAPTRAPGEF3KDM4EHTTATM | |
| SCHEMBL3445247 | 0.78 | RAPGEF3 (0.47) | MAPTRAPGEF3KDM4EHTTATM | |
| SCHEMBL16406354 | 0.78 | CA12 (0.55) | PDK2MAPTRAPGEF3BCHEMEN1 | |
| SCHEMBL21114051 | 0.78 | PDK2 (0.48) | PDK2MAPTGPR119KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175905-A1 | DIMER COMPOUNDS | Kesmalea Therapeutics Limited (GB) | 2024-08-29 | — | — | WO | disclosed |