Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OTC | P00480 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102609 | 0.96 | CA12 (0.37) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL3108218 | 0.92 | CA12 (0.35) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL3100745 | 0.90 | CA12 (0.36) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL3101435 | 0.88 | CA12 (0.35) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL3106054 | 0.88 | CA12 (0.38) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2987248 | 0.82 | OTC (0.40) | MEN1KMT2AOTC | |
| SCHEMBL2987243 | 0.82 | OTC (0.40) | MEN1KMT2AOTC | |
| SCHEMBL3108100 | 0.81 | CA12 (0.37) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL3098894 | 0.81 | CPB2 (0.33) | MEN1GAACYP2C9CYP2C19KMT2A | |
| SCHEMBL3087485 | 0.80 | GSR (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |