Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 10/20 | 0.89 |
| ▸ | EGFR | P00533 | 7/20 | 0.64 |
| ▸ | ITK | Q08881 | 5/20 | 0.64 |
| ▸ | BTK | Q06187 | 2/20 | 0.64 |
| ▸ | JAK2 | O60674 | 1/20 | 0.64 |
| ▸ | LYN | P07948 | 1/20 | 0.64 |
| ▸ | TEC | P42680 | 1/20 | 0.64 |
| ▸ | TXK | P42681 | 1/20 | 0.64 |
| ▸ | BMX | P51813 | 1/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.64 |
| ▸ | CD69 | Q07108 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656019 | 0.94 | SYK (1.00) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL30150629 | 0.93 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL23388258 | 0.93 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL12518303 | 0.85 | EGFR (0.88) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL23409017 | 0.83 | SYK (0.68) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL27020093 | 0.82 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL13166285 | 0.82 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL23409083 | 0.82 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL29665636 | 0.82 | SYK (0.77) | SYKEGFRITKBTKJAK2 | |
| SCHEMBL15814263 | 0.82 | SYK (0.74) | SYKEGFRITKBTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |