Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629199 | 0.90 | CA12 (0.66) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31124414 | 0.82 | CA12 (0.58) | CA12CA1CA2CA7CA13 | |
| SCHEMBL13778721 | 0.82 | CA12 (0.58) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31034747 | 0.82 | CA12 (0.58) | CA12CA1CA2CA7CA13 | |
| SCHEMBL20400993 | 0.80 | CA12 (0.56) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31034586 | 0.79 | CA12 (0.55) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31034597 | 0.79 | CA12 (0.55) | CA12CA1CA2CA7CA13 | |
| SCHEMBL15648180 | 0.79 | CA2 (1.00) | CA12CA1CA2CA7CA13 | |
| SCHEMBL13778590 | 0.78 | CA12 (0.54) | CA12CA1CA2CA7CA13 | |
| SCHEMBL31034686 | 0.78 | CA12 (0.58) | CA12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175999-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2024-08-29 | — | — | WO | disclosed |