Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034874 | 0.85 | HCRTR2 (0.46) | HCRTR2 | |
| SCHEMBL31034897 | 0.84 | HCRTR2 (0.41) | HCRTR2 | |
| SCHEMBL31035009 | 0.83 | HCRTR2 (0.46) | HCRTR2 | |
| SCHEMBL31034904 | 0.81 | HCRTR2 (0.42) | HCRTR2 | |
| SCHEMBL31034880 | 0.81 | HCRTR2 (0.53) | HCRTR2 | |
| SCHEMBL31034863 | 0.75 | HCRTR2 (0.49) | HCRTR2 | |
| SCHEMBL31034920 | 0.74 | HCRTR2 (0.51) | HCRTR2 | |
| SCHEMBL31034980 | 0.72 | HCRTR2 (0.42) | HCRTR2 | |
| SCHEMBL31034884 | 0.71 | HCRTR2 (0.38) | HCRTR2 | |
| SCHEMBL122218 | 0.70 | GPR119 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658660-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | Jazz Pharmaceuticals Ireland Limited (IE) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160822-A1 | MACROCYCLIC OREXIN RECEPTOR AGONISTS AND USES THEREOF | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-08-08 | — | — | WO | disclosed |